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Research Community


A Rich History of Genetic Research

Wisdom Health has been conducting research in the field of canine genetics for more than a decade starting with the initial canine genomics project in 1999 and the first canine breeder test in 2011. Today our technology powers some of the most comprehensive breed and genetic disease detection products on the market for breeders, veterinarian, consumers at home, and shelters.

Since the beginning, we have been passionate about advancing the science of companion animal genetics so that we can help owners understand the unique needs of their pets from the inside out. As we round the corner to 800,000 dogs tested and launch into testing our feline friends as well, we feel a great sense of gratitude for those pet owners and breeders who have been on this journey with us. The more we know about our pets the better we can plan for their individual needs. Simply put…working towards happier and healthier lives for our pets.



The World Leader in Companion Animal Genetic Testing

As part of the largest pet care company in the world, we are able to draw on research from some of the most extensive databases of canine behavior, health and nutritional information to develop our tests. This includes a genetic database of more than 15,000 purebred dogs, encompassing multiple continents and hundreds of breeds. In addition we hold the only commercial license in the United States from Washington State University for the use of the potentially lifesaving MDR1 multi-drug sensitivity test. Panel testing for genetic disease has allowed us to provide insight into presence and significance of genetic disease, making new discoveries in partnership with breeder communities for the benefit of pets worldwide.

Search Dog Foundation

MDR1 Technology Licensed From

Proud to Partner With

Peer Reviewed Journal Articles

A single IGF1 allele is a major determinant of small size in dogs
Science. 2007 Apr 6;316(5821):112-5
Sutter NB, Bustamante CD, Chase K, Gray MM, Zhao K, Zhu L, Padhukasahasram B, Karlins E, Davis S, Jones PG, Quignon P, Johnson GS, Parker HG, Fretwell N, Mosher DS, Lawler DF, Satyaraj E, Nordborg M, Lark KG, Wayne RK, Ostrander EA

Genome-wide SNP and haplotype analyses reveal a rich history underlying dog domestication
Nature. 2010 Apr 8;464(7290):898-902. Epub 2010 Mar 17
Vonholdt BM, Pollinger JP, Lohmueller KE, Han E, Parker HG, Quignon P, Degenhardt JD, Boyko AR, Earl DA, Auton A, Reynolds A, Bryc K, Brisbin A, Knowles JC, Mosher DS, Spady TC, Elkahloun A, Geffen E, Pilot M, Jedrzejewski W, Greco C, Randi E, Bannasch D, Wilton A, Shearman J, Musiani M, Cargill M, Jones PG, Qian Z, Huang W, Ding ZL, Zhang YP, Bustamante CD, Ostrander EA, Novembre J, Wayne RK

Population structure and inbreeding from pedigree analysis of purebred dogs
Genetics. 2008 May;179(1):593-601
Calboli FC, Sampson J, Fretwell N, Balding DJ

A web resource on DNA tests for canine and feline hereditary diseases
Vet J. 2013 Aug;197(2):182-7. Epub 2013 Apr 11
Slutsky J, Raj K, Yuhnke S, Bell J, Fretwell N, Hedhammar A, Wade C, Giger U

Single-nucleotide-polymorphism-based association mapping of dog stereotypes
Genetics. 2008 Jun;179(2):1033-44. Epub 2008 May 27
Jones P, Chase K, Martin A, Davern P, Ostrander EA, Lark KG

Genome wide analysis indicates genes for basement membrane and cartilage matrix proteins as candidates for hip dysplasia in Labrador Retrievers
PLoS One. 2014 Jan 30;9(1):e87735. eCollection 2014
Lavrijsen IC, Leegwater PA, Martin AJ, Harris SJ, Tryfonidou MA, Heuven HC, Hazewinkel HA

Genetic mapping of fixed phenotypes: disease frequency as a breed characteristic
2009 Jul-Aug;100 Suppl 1:S37-41. Epub 2009 Mar 25
Chase K, Jones P, Martin A, Ostrander EA, Lark KG. J Hered

Complex population structure in African village dogs and its implications for inferring dog domestication history
Proc Natl Acad Sci U S A. 2009 Aug 18;106(33):13903-8
Boyko AR, Boyko RH, Boyko CM, Parker HG, Castelhano M, Corey L, Degenhardt JD, Auton A, Hedimbi M, Kityo R, Ostrander EA, Schoenebeck J, Todhunter RJ, Jones P, Bustamante CD